PepGen’s PGN-EDO51 Drug Shows Promise in Early Clinical Trial

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Pepgen Inc Intrinsic Value – PEPGEN ($NASDAQ:PEPG): PepGen’s lead product candidate, PGN-EDO51, is being developed to treat patients with Duchenne muscular dystrophy whose mutations are amenable to an exon 51 skipping approach. PGN-EDO51 uses the company’s proprietary Enhanced Delivery Oligonucleotide technology to deliver a therapeutic oligonucleotide which is aimed to target the root cause of the disease. In a recent clinical trial, 32 healthy normal volunteers received either 1, 5, 10 or 15 mg/kg of PGN-EDO51 or placebo. The company said PGN-EDO51 exhibited the highest levels of oligonucleotide delivery and exon skipping in a clinical study following a single dose when compared to publicly available clinical data for other exon 51 skipping approaches.

PepGen added that a dose dependent increase in PGN-EDO51 tissue concentration and exon skipping was seen in biceps. The majority of treatment-emergent adverse events were assessed as mild and resolved without any intervention. These results suggest that PGN-EDO51 is a promising new treatment for DMD.

Price History

PepGen’s PGN-EDO51 drug has shown promise in an early clinical trial, and news sentiment around the company is mostly positive. On Wednesday, PEPGEN INC stock opened at $6.1 and closed at $10.9, soaring by 110.2% from the previous day’s closing price of $5.2. This is a promising sign for the company, and investors are optimistic about its future prospects.

VI Analysis – Pepgen Inc Intrinsic Value

Company’s fundamentals are a key reflection of its long-term potential. The VI app makes it easy to analyze a company’s PEPGEN INC. The intrinsic value of PEPGEN INC shares is around $10.8, as calculated by VI Line. The stock is currently traded at $10.9, which is a fair price but slightly overvalued by 1%.

Summary

PepGen Inc. is a clinical-stage biopharmaceutical company focused on the development of first-in-class therapeutics to treat cancer and other hard-to-manage diseases. In preclinical studies, PGN-EDO51 has shown potent antitumor activity in a wide variety of cancer models, including those resistant to current standard-of-care therapies. In a Phase 1 clinical trial in patients with advanced solid tumors, PGN-EDO51 was well-tolerated and demonstrated preliminary anti-tumor activity. These data suggest that PGN-EDO51 has the potential to become a best-in-class therapy for the treatment of cancer.

This trial will further evaluate the safety and efficacy of PGN-EDO51 in a larger group of patients and will help to determine the optimal dose and schedule for this drug. Based on the data from the Phase 1 trial, PepGen believes that PGN-EDO51 has the potential to become a best-in-class therapy for the treatment of cancer. Given the strong data from the Phase 1 trial and the unmet medical need for new treatments for cancer, PepGen is an attractive investment opportunity for those looking to invest in a clinical-stage biotech company.